VPN Disconnected on Windows 10 Pro

Apologies, been on holiday since 22nd July. I've now had chance to look at your comments. I can confirm that I can access the NAS through the ReadyCLOUD portal. I am using BitDefender AV and Windows Firewall on one PC and have McAfee Internet Security on all my other devices. 

On the PC, I've disabled BitDefender but am unable to disable Windows Firewall as it's a domained PC and Windows Firewall is controlled by group policy. However, I've confirmed that 'ReadyNASRemote' is allowed through Domain, Private and Public networks. This did not work on the PC, the ReadyCLOUD application on the PC still shows 'Online (VPN Disconnected)'.

All four of my other Windows 10 Pro devices are not domained, I've disabled McAfee Internet Security completely (both Firewall and AV components) on all four devices but these also have the same error 'Online (VPN Disconnected)'.

On my one device running Windows 10 Home, this has McAfee Internet Security installed and ReadyCLOUD runs and works without issue with McAfee Internet Security installed. On my Windows 8.1 laptop, also with McAfee Internet Security installed, ReadyCLOUD also runs and works without issue.