RBR750 won't apply network settings

What do you mean wont apply network settings to laptops? 

Are they getting an IP address? 

What personal devices do you have? 

What OS platform is on the laptops? 
Are they wireless or ethernet connected? 

Be sure to disable any MAC Address randomizers on phones and pads while at home:

https://community.netgear.com/kb/en-orbi-knowledge-sharing/netgear-mobile-applications-and-androidapplewindows-devices-faq/2457046

What Firmware version is currently loaded?

What is the Mfr and model# of the Internet Service Providers modem/ONT the NG router is connected too?

Be sure your using a good quality LAN cable between the modem and router. CAT6 is recommended. 

Is the RBR in router or AP mode? 

How many RBS are deployed? 

RBS750s? 

What is the size of your home? Sq Ft?

What is the distance between the router 📡 and satellite(s)🛰️? 30 feet or more is recommended in between RBR 📡 and RBS 🛰️ to begin with depending upon building materials when wired or wirelessly connected.

https://kb.netgear.com/31029/Where-should-I-place-my-Orbi-satellite ‌‌🛰

Does this happen with the RBS turned OFF? 

Does this happen with both wireless and wired devices? 

What channel configurations are currently set on the router?  

Try disabling the following and see:

Armor, Smart Parental Controls or Circle, IPv6, Protection Engine, Traffic Meter.

Has a power off for 1 minute then back ON with the ISP modem and router and satellite(s) been performed since last update?

Be sure to restart your network in this sequence:

Turn off and unplug modem.

Turn off router and computers.

Plug in and turn on modem. Wait 2 minutes for it to connect.

Turn on the router and wait 2 minutes for it to connect.

Turn on computers and rest of network.