Connectivity issues with my RAX80

What Firmware version is currently loaded?
What is the Mfr and model# of the Internet Service Providers modem/ONT the NG router is connected too?
Be sure your using a good quality LAN cable between the modem and router. CAT6A STP is recommended. 

What channels are you using? Try setting manual channel 1, 6 or 11 on 2.4Ghz and 40 to 48 channel on 5Ghz.
Any Wifi Neighbors near by? If so, how many?

Try disabling the following and see:
Armor, Smart Parental Controls or Circle, Traffic Meter.

If all else fails, Factory reset and a complete pull of the power adapters for a period of time after the factory reset then walk thru the setup wizard and setup from scratch with a wired PC and web browser. https://kb.netgear.com/22697/How-do-I-install-my-NETGEAR-router-using-the-router-web-interface
Recommend setting the default DHCP IP address pool range to the following after applying and a factory reset: 192.168.#.100 to 192.168.#.200.
https://kb.netgear.com/24089/How-do-I-specify-the-pool-of-IP-addresses-assigned-by-my-Nighthawk-router
https://kb.netgear.com/25722/How-do-I-reserve-an-IP-address-on-my-NETGEAR-router
I would power OFF the ISP modem for 1 minute. Factory reset the router and power it off. Power ON the ISP modem and let it sync. Then power ON the router and walk thru the setup wizard again using a wired PC and a web browser.
Press the back reset button for 10 seconds then release. 
https://kb.netgear.com/9665/How-do-I-perform-a-factory-reset-on-my-NETGEAR-router
Or use the ERASE button on the routers web page to factory reset the router:
https://kb.netgear.com/24233/How-do-I-erase-the-configuration-settings-on-my-Nighthawk-router

Thanks to all the members and gurus really appreciated.

Routing: NETGEAR RAX43 - Firmware: v1.0.15.128 (1 Gbps down, 40 Mbps up)
Switching: 2x NETGEAR 8-ports (GS108v4) / 1x NETGEAR 16-ports (GS116v2) / 2x NETGEAR PL1000v2
Desktop: AMD Ryzen 9 5900X - Server: Medical Clinic TX - NAS: Intel Pentium G4400, 20 TB