Can the iSCSI Initiator Listen on One LAN Port Only?

Binding to specific NICs/IPs was not part of the feature set. It would be possible, but would modifying the iSCSI /sys/class/ definitions, which is not supported.

Thank you for the quick response Chirpa. At least now I know its unsupported and that feature will likely never make it into the product.

Cheers,
Mark.

It may get into 6.0 at some point (not a feature there either right now), but NTGR has said that the existing x86 line won't receive that OS update.

If you use the ESXi iSCSI initiator, you can specify which Ethernet interface the iSCSI storage adapter can use. So, you can restrict iSCSI to just one interface. If you create an isolated network (and better yet isolated broadcast domain) for your iSCSI traffic and not route between this isolated network/broadcast domain and the LAN where your ReadyNAS port for regular traffic is connected, you will be able to not push any iSCSI traffic to the ReadyNAS port that you dedicated to regular (non-iSCSI) traffic. To create an isolated broadcast domain, you can do one of four things:
a. Direct cable between the ESXi box's Ethernet port dedicated to iSCSI and the ReadyNAS Ethernet port dedicated to iSCSI.
b. A separate VLAN in your switch dedicated to iSCSI where you connect ESXi box's Ethernet port(s) dedicated to iSCSI and the ReadyNAS port dedicated to iSCSI.
c. Two separate switches: one dedicated to iSCSI, and the other one dedicated to your regular LAN traffic.
d. Least preferable - one broadcast domain for both your iSCSI and non-iSCSI traffic.

The trick to this solution is to prevent your box where the iSCSI initiator is installed from using its interface(s) on the non-iSCSI network for iSCSI traffic.

This solution does not prevent your ReadyNAS from advertising its iSCSI target out of both of its Ethernet ports, but because your iSCSI initiator box only sends its iSCSI traffic to the network where only one of the ReadyNAS's Ethernet ports is connected, the ReadyNAS does not use the other Ethernet port for iSCSI traffic (except for the iSCSI target advertising). Obviously, the two Ethernet ports on the ReadyNAS will have to be in two different subnets for this solution to work.